JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Gout

Obligatory

Must not donate.

Discretionary

Accept if:

a) For BM donation


b) For PBSC: Discuss with DCSO. See ‘Additional Information’

Additional Information

Gout is an acute arthritis caused by build-up of uric acid crystals in the joint space. There have been reports of severe exacerbation of gout following administration of G-CSF.


In the interests of donor protection, caution should be exercised before considering donors with gout for PBSC donation. In these circumstances, donors should be counselled about the possibility of exacerbation of their condition and consent to this before proceeding to receive G-CSF.


Affected individuals should be excluded from PBSC donation unless permitted by DCSO based on individual risk assessment.

Reason for Change

Exclude affected individuals from donation of PBSC unless permitted by DCSO.

Update Information

This entry was last updated in
TDSG-BM Edition 203, Release 54