JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Bleeding Disorder

Includes

Christmas disease, clotting factor treatment, factor deficiency (including carriers), haemophilia and Von Willebrand's disease.

1. Affected Individual
Obligatory

Must not donate if:
a) Treated with blood derived coagulation factor concentrates.

b) There is a history of excessive bleeding or bruising.

Discretionary

Carrier state:
This does not necessarily prevent donation. Refer to a 'Designated Clinical Support Officer' who will liaise with the haematologist that investigated the donor.

See if Relevant

Platelet Disorder
Transfusion

Additional Information

People who have received blood derived coagulation concentrates (these are made from the blood of many hundreds of individual donors) may have been put at risk of infections that can be passed through donations.

They represent one of the groups of individuals within whom emerging infections have spread before they have been recognized. This was the case with HIV and HCV infection. Because of this, the law requires that they are permanently excluded from becoming donors. It can be many years before any infection shows itself.

If someone has had problems with bleeding or bruising, taking blood from them could be harmful.

Some people with the carrier state (trait) for some bleeding disorders may themselves be at risk of bleeding. Also, if their blood is used to make fresh frozen plasma, this may not have enough of the clotting factor in it to be useful to the person receiving it.

Reason for change

See below

2. Family Members, Carers and Sexual Partners of Individuals Treated with Blood Derived Coagulation Factor Concentrates
Obligatory

Must not donate if:
a) Treated with blood derived coagulation factor concentrates.

b) A sexual partner, or former sexual partner, of a person treated with blood derived coagulation factor concentrates.

c) Less than four months after the date of an inoculation injury with either blood derived coagulation factor concentrates, or from blood contamination from an affected individual.

d) Diagnosed as affected (even mildly) by the disorder.

Discretionary

If three months or more from the last sexual contact, accept.

See if Relevant

Non-Consented Exposure to Human Body Fluids
Transfusion

Additional Information

Blood derived coagulation concentrates are made from the blood of many hundreds of individual donors. They may put recipients at risk of infections that can be passed through blood. This risk may be shared by their sexual partners and anyone suffering an inoculation injury.

Many bleeding disorders are inherited. Family members that are blood relations may be affected by the bleeding disorder. They could be at risk of excessive bleeding or bruising. Most close blood relations would have been screened by a haematologist from whom additional information may be available.

Waiting three or four months from the last sexual contact or inoculation injury helps to ensure that the infections tested for by the Blood and Tissues Services will be picked up. 

 

This guidance presumes that a validated NAT test for hepatitis C is negative. If this test is stopped, the guidance will change.

Information

Part of this entry is a requirement of the Blood Safety and Quality Regulations 2005.

Reason for change

See below

Additional Information

The Northern Ireland Health Minister has announced a relaxation of the deferrals for MSM and other high-risk activities which will reduce from 12 months to three months. This is due to be implemented on 1st June 2020. The changes are in line with the other UK transfusion services and the recommendations of the SaBTO Donor Selection Criteria Review Report (2017).

Donor Information

If you wish to obtain more information regarding a personal medical issue please contact your National Help Line.

Please do not contact this web site for personal medical queries, as we are not in a position to provide individual answers.

Update Information

This entry was last updated in DSG-WB Edition 203, Release 50