JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee
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Xenotransplantation

Includes

Heterografts, non-human organ perfusion, xenografts and xenotransplant recipients.

Definitions

Xenotransplantation:
Any procedure that involves the transplantation, implantation, or infusion into a human recipient of either (a) live cells, tissues, or organs from a non-human animal source, or (b) human body fluids, cells, tissues, or organs that have had ex vivo contact with live, non-human animal cells, tissues, or organs. Xenotransplantation products include live cells, tissues and organs.

Biological products, drugs, or medical devices sourced from non-living cells, tissues or organs from non-human animals including, but not limited to, porcine insulin, porcine heart valves and acellular porcine collagen matrix are not considered xenotransplantation products.

Inoculation injuries from non human sources are not considered to be Xenotransplants.

1. Recipient
Obligatory

Must not donate if:
Material from a living non-human animal source has been directly or indirectly in contact with the donor's blood supply. This does not include animal bites.

See if Relevant

Animal Bite (Non-Human)
Non-Consented Exposure to Human Body Fluids

Additional Information

Exposure to non-human animal material, particularly when the person exposed is immunosuppressed, may result in unusual infections, that would not normally affect humans, being passed on to recipients of donated material. Inoculation injury, involving non-human animals, does not fall into the category of xenotransplantation

2. Current or Former Sexual Partner of Xenotransplant Recipient
Obligatory

Must not donate.

Additional Information

Sexual partners of individuals who have received a xenotransplant may potentially be at risk of acquiring an unusual infection that may be passed on by donated material. Because the duration of any risk is not known, deferral must be permanent.

Information

This is a requirement of the Blood Safety and Quality Regulations 2005.

Reason for change

Reference to specific products has been removed from the Definitions section

Donor Information

If you wish to obtain more information regarding a personal medical issue please contact your National Help Line.

Please do not contact this web site for personal medical queries, as we are not in a position to provide individual answers.

Update Information

This entry was last updated in:
DSG-WB Edition 203, Release 10 Issue 67