JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Appendix II International Haemovigilance Network categories for donor adverse events

AII.1 Complications mainly with local symptoms

AII.1.1 Complications mainly characterised by the occurrence of blood outside the vessels

Haematoma

A haematoma is an accumulation of blood in the tissues outside the vessels.

Arterial puncture

Arterial puncture is a puncture of the brachial artery or of one of its branches by the needle used for bleeding of the donor.

Delayed bleeding

Delayed bleeding is spontaneous recommencement of bleeding from the venepuncture site, which occurs after the donor has left the donation site.

AII.1.2 Complications mainly characterised by pain

Nerve irritation

Irritation of a nerve by pressure from a haematoma.

Nerve injury

Injury of a nerve by the needle at insertion or withdrawal.

Tendon injury

Injury of a tendon by the needle.

Painful arm

Cases characterised mainly by severe local and radiating pain in the arm used for the donation and arising during or within hours following donation, but without further details to permit classification in one of the already more specific categories mentioned above.

AII.1.3 Other kinds of categories with local symptoms

Thrombophlebitis

Inflammation in a vein associated with a thrombus.

Allergy (local)

Allergic type skin reaction at the venepuncture site caused by allergens in solutions used for disinfection of the arm or allergens from the needle.

AII.2 Complications mainly with generalised symptoms

AII.2.1 Vasovagal reaction

A vasovagal reaction is a general feeling of discomfort and weakness with anxiety, dizziness and nausea, which may progress to loss of consciousness (faint).

AII.2.2 Immediate vasovagal reaction

Symptoms occurred before donor has left the donation site.

AII.2.3 Immediate vasovagal reaction with injury

Injury caused by falls or accidents in donors with a vasovagal reaction and unconsciousness before donor has left the donation site.

AII.2.4 Delayed vasovagal reaction

Symptoms occurred after donor has left the donation site.

AII.2.5 Delayed vasovagal reaction with injury

Injury caused by falls or accidents in donors with a vasovagal reaction and unconsciousness after donor has left the donation site.

AII.3 Complications related to apheresis

AII.3.1 Citrate reaction

All.3.2 Haemolysis

AII.3.3 Generalised allergic reaction

AII.3.4 Air embolism

AII.4 Other complications related to blood donation