JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Fresh Frozen Plasma (FFP)

  • Estcourt LJ, Desborough M, Doree C, Hopewell S, Trivella M, Stanworth SJ. 
    Plasma transfusions prior to lumbar punctures and epidural catheters for people with abnormal coagulation (Protocol). 
    Cochrane Database of Systematic Reviews 2017;(1): CD012497.
    Full text: Wiley (subscription may be required)

  • Hall DP, Estcourt LJ, Doree C, Hopewell S, Trivella M, Walsh TS .
    Plasma transfusions prior to insertion of central lines for patients with abnormal coagulation.
    Cochrane Database Systematic Review 2016; (9): CD011756.
    Access abstract: PubMed /  full text: Wiley (subscription may be required)

  • Desborough M, Sandu R, Brunskill SJ, Doree C, Trivella M, Montedori A, Abraha I, Stanworth S.
    Fresh frozen plasma for cardiovascular surgery
    Cochrane Database of Systematic Reviews 2015;(7):CD007614.
    Access abstract: PubMed /  full text: Wiley (subscription may be required)

  • Yang L, Stanworth S, Hopewell S, Doree C, Murphy M.
    Is fresh-frozen plasma clinically effective? An update of a systematic review of randomized controlled trials.
    Transfusion 2012; 52(8):1673-86.
    Access abstract: PubMed / full text: Wiley (subscription required)

  • Stanworth SJ, Grant-Casey J, Lowe D, Laffan M, New H, Murphy MF, Allard S.
    The use of fresh-frozen plasma in England: high levels of inappropriate use in adults and children.
    Transfusion 2011; 51(1): 62-70.
    Access abstract: PubMed / full text: Wiley (subscription required)

  • Stanworth SJ, Hyde CJ, Murphy MF.
    Evidence for indications of fresh frozen plasma.
    Transfusion clinique et biologique 2007; 14(6): 551-556.
    Access abstract: PubMed / full text: ScienceDirect (subscription required) 

  • Stanworth SJ.
    The evidence-based use of FFP and cryoprecipitate for abnormalities of coagulation tests and clinical coagulopathy.
    Hematology / American Society of Hematology Education Program 2007:179-186.
    Access abstract: PubMed / full text: here (freely available)

  • Stanworth SJ, Brunskill SJ, Hyde CJ, Murphy MF, McClelland DBL.
    Appraisal of the evidence for the clinical use of FFP and plasma fractions.
    Best Practice and Research: Clinical Haematology 2006; 19(1): 67-82.
    Access abstract: PubMed / full text: ScienceDirect (subscription required) 

  • Stanworth SJ, Walsh TS.
    Fresh frozen plasma: friend or faux pas in critical illness?
    Critical Care Medicine 2005; 33 (11): 2714-6.
    No abstract available / full text: LWW (subscription required)

  • Stanworth SJ, Brunskill SJ, Hyde CJ, McClelland DB, Murphy MF.
    Is fresh frozen plasma clinically effective? A systematic review of randomised controlled trials.
    British Journal of Haematology 2004; 126(1): 139-52.
    Access abstract: PubMed / full text: Wiley (subscription required)