JPAC Joint United Kingdom (UK) Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee

Platelet Transfusion

  • Desborough M, Estcourt LJ, Doree C, Trivella M, Hopewell S, Stanworth SJ,Murphy MF. 
    Alternatives, and adjuncts, to prophylactic platelet transfusion for people with haematological malignancies undergoing intensive chemotherapy or stem cell transplantation.
    Cochrane Database of Systematic Reviews 2016;(8): CD010982.
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  • Desborough M, Hadjinicolaou AV, Chaimani A, Trivella M, Vyas P, Doree C, Hopewell S, Stanworth SJ,Estcourt LJ. 
    Alternative agents to prophylactic platelet transfusion for preventing bleeding in people with thrombocytopenia due to chronic bone marrow failure: a meta-analysis and systematic review.
    Cochrane Database of Systematic Reviews 2016;(10): CD012055.
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  • Ashraf A, Hadjinicolaou AV, Doree C, Hopewell S, Trivella M, Estcourt LJ.
    Comparison of a therapeutic-only versus prophylactic platelet transfusion policy for people with congenital or acquired bone marrow failure disorders (protocol).
    Cochrane Database of Systematic Reviews 2016; (9):CD012342.
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  • Desborough MJ, Smethurst PA, Estcourt LJ, Stanworth SJ.
    Alternatives to allogeneic platelet transfusion.
    British Journal of Haematology 2016, epub. doi: 10.1111/bjh.14338.
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  • Desborough M, Estcourt LJ, Doree C, Trivella M, Hopewell S, Stanworth SJ, Murphy MF.
    Alternatives, and adjuncts, to prophylactic platelet transfusion for people with  haematological malignancies undergoing intensive chemotherapy or stem cell transplantation.
    Cochrane Database of Systematic Reviews 2016;(8):CD010982.
    Access abstract: PubMed / full text: Wiley (subscription may be required)

  • Desborough M, Estcourt LJ, Chaimani A, Doree C, Hopewell S, Trivella M, Hadjinicolaou AV, Vyas P, Stanworth SJ.
    Alternative agents versus prophylactic platelet transfusion for preventing bleeding in patients with thrombocytopenia due to chronic bone marrow failure: a network meta-analysis and systematic review (protocol).
    Cochrane Database of Systematic Reviews 2016;(1): CD012055.
    Access abstract: PubMed / full text: PMC (freely available)

  • Estcourt LJ, Ingram C, Doree C, Hopewell S, Trivella M, Stanworth SJ.
    Use of platelet transfusions prior to lumbar punctures or epidural anaesthesia for the prevention of complications in people with thrombocytopenia.
    Cochrane Database of Systematic Reviews 2016;(5):CD011980.
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  • Estcourt LJ, Desborough M, Hopewell S, Stanworth SJ.
    Comparison of different platelet transfusion thresholds prior to insertion of central lines in patients with thrombocytopenia (protocol).
    Cochrane Database of Systematic Reviews 2015; (12): CD011771.
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  • Estcourt LJ, Stanworth SJ, Doree C, Hopewell S, Trivella M, Murphy MF.
    Comparison of different platelet count thresholds to guide administration of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after chemotherapy or stem cell transplantation.

    Cochrane Database of Systematic Reviews 2015;(11):CD010983.
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  • Estcourt LJ, Stanworth S, Doree C, Trivella M, Hopewell S, Blanco P, Murphy MF.
    Different doses of prophylactic platelet transfusion for preventing bleeding in people with haematological disorders after myelosuppressive chemotherapy or stem cell transplantation.
    Cochrane Database of Systematic Reviews 2015;(10):CD010984.
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  • Crighton GL, Estcourt LJ, Wood EM, Trivella M, Doree C, Stanworth S.
    A therapeutic-only versus prophylactic platelet transfusion strategy for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation
    Cochrane Database of Systematic Reviews 2015;(9):CD010981.
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  • Estcourt LJ, Gregg R, Stanworth S, Doree C, Trivella M, Murphy MF, Tinmouth A.
    Alternative agents versus prophylactic platelet transfusion for preventing bleeding in patients with haematological disorders after chemotherapy or stem cell transplantation (protocol).
    Cochrane Database of Systematic Reviews 2014;(3): CD010982.
    Access abstract: PubMed / full text: PMC (freely available)

  • Estcourt LJ, Pinchon D, Symington E, Kelly AM, Doree C, Brunksill S, Glidewell L, Stanworth S.
    Does bleeding affect patient-reported outcome measures in patients with myolodysplasia or haematologic malignancies: a systematic review.
    Transfusion 2014;54(4):1166-79.
    Access abstract: PubMed / full text: Wiley (subscription required)

  • Butler C, Doree C, Estcourt LJ, Trivella M, Hopewell S, Brunskill SJ, Stanworth S, Murphy MF.
    Pathogen-reduced platelets for the prevention of bleeding.
    Cochrane Database of Systematic Reviews 2013;(3):CD009072.
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  • Estcourt LJ, Heddle N, Kaufman R, McCullough J, Murphy MF, Slichter S, Wood EM, Stanworth SJ on behalf of the BEST Collaborative.
    The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions.
    Transfusion 2013; 53(7):1531-1543.
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  • Estcourt LJ, Birchall J, Lowe D, Grant-Casey J, Rowley M, Murphy MF.
    Platelet transfusions in haematology patients: are we using them appropriately?
    Vox Sanguinis 2012; 103(4): 284-93.
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  • Estcourt L, Stanworth S, Doree C, Hopewell S, Murphy MF, Tinmouth A, Heddle N.
    Prophylactic platelet transfusion for prevention of bleeding in patients with haematological disorders after chemotherapy and stem cell transplantation.
    Cochrane Database of Systematic Reviews 2012; (5): CD004269.
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  • Estcourt LJ, Stanworth SJ, Murphy MF.
    Platelet transfusions for patients with haematological malignancies: who needs them?
    British Journal of Haematology 2011; 154(4): 425-40.
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  • Estcourt LJ, Stanworth SJ, Murphy MF.
    Prophylactic platelet transfusions.
    Current Opinion in Hematology 2010; 17(5):411-17.
    Access abstract: PubMed / full text: LWW (subscription required)

  • Stanworth SJ, Hyde C, Brunskill S, Murphy M.
    Platelet transfusion prophylaxis for patients with haematological malignancies: where to now?
    British Journal of Haematology 2005; 131(5): 588-95.
    Access abstract: PubMed / full text: Wiley (subscription required)